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A novel site comes into sight

Oxysterols modulate the Hedgehog signalling pathway by binding a novel site on the membrane protein Smoothened, which may offer new options for the treatment of cancers linked to this pathway.

Detalles Bibliográficos
Autores principales: Wang, Yu, McMahon, Andrew P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847883/
https://www.ncbi.nlm.nih.gov/pubmed/24302574
http://dx.doi.org/10.7554/eLife.01680