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A novel site comes into sight

Oxysterols modulate the Hedgehog signalling pathway by binding a novel site on the membrane protein Smoothened, which may offer new options for the treatment of cancers linked to this pathway.

Detalles Bibliográficos
Autores principales: Wang, Yu, McMahon, Andrew P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847883/
https://www.ncbi.nlm.nih.gov/pubmed/24302574
http://dx.doi.org/10.7554/eLife.01680
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author Wang, Yu
McMahon, Andrew P
author_facet Wang, Yu
McMahon, Andrew P
author_sort Wang, Yu
collection PubMed
description Oxysterols modulate the Hedgehog signalling pathway by binding a novel site on the membrane protein Smoothened, which may offer new options for the treatment of cancers linked to this pathway.
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spelling pubmed-38478832013-12-04 A novel site comes into sight Wang, Yu McMahon, Andrew P eLife Biochemistry Oxysterols modulate the Hedgehog signalling pathway by binding a novel site on the membrane protein Smoothened, which may offer new options for the treatment of cancers linked to this pathway. eLife Sciences Publications, Ltd 2013-12-03 /pmc/articles/PMC3847883/ /pubmed/24302574 http://dx.doi.org/10.7554/eLife.01680 Text en Copyright © 2013, Wang and McMahon http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Biochemistry
Wang, Yu
McMahon, Andrew P
A novel site comes into sight
title A novel site comes into sight
title_full A novel site comes into sight
title_fullStr A novel site comes into sight
title_full_unstemmed A novel site comes into sight
title_short A novel site comes into sight
title_sort novel site comes into sight
topic Biochemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847883/
https://www.ncbi.nlm.nih.gov/pubmed/24302574
http://dx.doi.org/10.7554/eLife.01680
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