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A novel site comes into sight
Oxysterols modulate the Hedgehog signalling pathway by binding a novel site on the membrane protein Smoothened, which may offer new options for the treatment of cancers linked to this pathway.
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847883/ https://www.ncbi.nlm.nih.gov/pubmed/24302574 http://dx.doi.org/10.7554/eLife.01680 |
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author | Wang, Yu McMahon, Andrew P |
author_facet | Wang, Yu McMahon, Andrew P |
author_sort | Wang, Yu |
collection | PubMed |
description | Oxysterols modulate the Hedgehog signalling pathway by binding a novel site on the membrane protein Smoothened, which may offer new options for the treatment of cancers linked to this pathway. |
format | Online Article Text |
id | pubmed-3847883 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | eLife Sciences Publications, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-38478832013-12-04 A novel site comes into sight Wang, Yu McMahon, Andrew P eLife Biochemistry Oxysterols modulate the Hedgehog signalling pathway by binding a novel site on the membrane protein Smoothened, which may offer new options for the treatment of cancers linked to this pathway. eLife Sciences Publications, Ltd 2013-12-03 /pmc/articles/PMC3847883/ /pubmed/24302574 http://dx.doi.org/10.7554/eLife.01680 Text en Copyright © 2013, Wang and McMahon http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Biochemistry Wang, Yu McMahon, Andrew P A novel site comes into sight |
title | A novel site comes into sight |
title_full | A novel site comes into sight |
title_fullStr | A novel site comes into sight |
title_full_unstemmed | A novel site comes into sight |
title_short | A novel site comes into sight |
title_sort | novel site comes into sight |
topic | Biochemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847883/ https://www.ncbi.nlm.nih.gov/pubmed/24302574 http://dx.doi.org/10.7554/eLife.01680 |
work_keys_str_mv | AT wangyu anovelsitecomesintosight AT mcmahonandrewp anovelsitecomesintosight AT wangyu novelsitecomesintosight AT mcmahonandrewp novelsitecomesintosight |