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Dengue 2 infection of HepG2 liver cells results in endoplasmic reticulum stress and induction of multiple pathways of cell death

BACKGROUND: A number of studies have implicated the direct involvement of the liver in dengue virus (DENV) infection, and it has been widely shown that liver cells subsequently undergo apoptosis. The mechanism by which liver cells undergo apoptosis in response to DENV infection remains unclear. To p...

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Detalles Bibliográficos
Autores principales: Thepparit, Chutima, Khakpoor, Atefeh, Khongwichit, Sarawut, Wikan, Nitwara, Fongsaran, Chanida, Chingsuwanrote, Pimjai, Panraksa, Patcharee, Smith, Duncan R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847886/
https://www.ncbi.nlm.nih.gov/pubmed/24034452
http://dx.doi.org/10.1186/1756-0500-6-372