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PKA regulatory subunit R2B is required for murine and human adipocyte differentiation

Adipogenesis is a complex process modulated by several factors, including cAMP signaling. The main cAMP target is protein kinase A (PKA), a tetrameric enzyme with four regulatory subunits showing tissue-specific expression and function: PRKAR2B is the main regulatory subunit in adipose tissue in mic...

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Detalles Bibliográficos
Autores principales: Peverelli, Erika, Ermetici, Federica, Corbetta, Sabrina, Gozzini, Ettore, Avagliano, Laura, Zappa, Marco A, Bulfamante, Gaetano, Beck-Peccoz, Paolo, Spada, Anna, Mantovani, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioScientifica 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847920/
https://www.ncbi.nlm.nih.gov/pubmed/24145613
http://dx.doi.org/10.1530/EC-13-0049