Cargando…

PKA regulatory subunit R2B is required for murine and human adipocyte differentiation

Adipogenesis is a complex process modulated by several factors, including cAMP signaling. The main cAMP target is protein kinase A (PKA), a tetrameric enzyme with four regulatory subunits showing tissue-specific expression and function: PRKAR2B is the main regulatory subunit in adipose tissue in mic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peverelli, Erika, Ermetici, Federica, Corbetta, Sabrina, Gozzini, Ettore, Avagliano, Laura, Zappa, Marco A, Bulfamante, Gaetano, Beck-Peccoz, Paolo, Spada, Anna, Mantovani, Giovanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioScientifica 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847920/ https://www.ncbi.nlm.nih.gov/pubmed/24145613 http://dx.doi.org/10.1530/EC-13-0049

Ejemplares similares

Protein Kinase A Regulatory Subunits in Human Adipose Tissue: Decreased R2B Expression and Activity in Adipocytes From Obese Subjects
por: Mantovani, Giovanna, et al.
Publicado: (2009)

A Novel Mechanism Regulating Dopamine Receptor Type 2 Signal Transduction in Pituitary Tumoral Cells: The Role of cAMP/PKA-Induced Filamin A Phosphorylation
por: Mangili, Federica, et al.
Publicado: (2021)

MON-465 SST2 Trafficking Through The Cytoskeleton: Role Of Scaffolding Proteins Filamin A And β-arrestin 2
por: Treppiedi, Donatella, et al.
Publicado: (2019)

Stem Cells in Pituitary Tumors: Experimental Evidence Supporting Their Existence and Their Role in Tumor Clinical Behavior
por: Mantovani, Giovanna, et al.
Publicado: (2019)

SAT-566 Cofilin Is a Mediator of RET-Promoted Medullary Thyroid Carcinoma Cell Migration, Invasion and Proliferation
por: Peverelli, Erika, et al.
Publicado: (2019)

The testis-specific Cα2 subunit of PKA is kinetically indistinguishable from the common Cα1 subunit of PKA
por: Vetter, Maike M, et al.
Publicado: (2011)

Role of filamin A in the pathogenesis of neuroendocrine tumors and adrenal cancer
por: Treppiedi, Donatella, et al.
Publicado: (2022)

Molecular mechanisms involved in somatostatin receptor regulation in corticotroph tumors: the role of cytoskeleton and USP8 mutations
por: Peverelli, Erika, et al.
Publicado: (2022)

Acute Stimulation of White Adipocyte Respiration by PKA-Induced Lipolysis
por: Yehuda-Shnaidman, Einav, et al.
Publicado: (2010)

SUN-213 The Role of Filamin A (FLNA) in the Regulation of Insulin-Like Growth Factor System in Adrenocortical Carcinomas
por: Peverelli, Erika, et al.
Publicado: (2020)

PKA regulation of neuronal function requires the dissociation of catalytic subunits from regulatory subunits
por: Xiong, Wei-Hong, et al.
Publicado: (2023)

Adipocyte HIF2α functions as a thermostat via PKA Cα regulation in beige adipocytes
por: Han, Ji Seul, et al.
Publicado: (2022)

Integrating molecular and structural findings: Wnt as a possible actor in shaping cognitive impairment in Cornelia de Lange syndrome
por: Avagliano, Laura, et al.
Publicado: (2017)

SAT-312 Beta-Arrestin 2 Is Required for Dopamine Receptor Type 2 Inhibitory Effects on Akt Phosphorylation and Cell Proliferation in Pituitary Tumors
por: Mangili, Federica, et al.
Publicado: (2020)

Autophagy and Human Parturition: Evaluation of LC3 Expression in Placenta from Spontaneous or Medically Induced Onset of Labor
por: Avagliano, Laura, et al.
Publicado: (2013)

The Catalytic Subunit β of PKA Affects Energy Balance and Catecholaminergic Activity
por: London, Edra, et al.
Publicado: (2019)

β-adrenergic receptor signaling evokes the PKA-ASK axis in mature brown adipocytes
por: Hattori, Kazuki, et al.
Publicado: (2020)

CFTR regulates brown adipocyte thermogenesis via the cAMP/PKA signaling pathway
por: Choi, Kyung-Mi, et al.
Publicado: (2023)

Identification, cloning and characterization of a novel 47 kDa murine PKA C subunit homologous to human and bovine Cβ2
por: Funderud, Ane, et al.
Publicado: (2006)

Evolutionary Paths of the cAMP-Dependent Protein Kinase (PKA) Catalytic Subunits
por: Søberg, Kristoffer, et al.
Publicado: (2013)

Evolution of the cAMP-dependent protein kinase (PKA) catalytic subunit isoforms
por: Søberg, Kristoffer, et al.
Publicado: (2017)

Phosphorylation of protein kinase A (PKA) regulatory subunit RIα by protein kinase G (PKG) primes PKA for catalytic activity in cells
por: Haushalter, Kristofer J., et al.
Publicado: (2018)

Reevaluation of Acromegalic Patients in Long-Term Remission according to Newly Proposed Consensus Criteria for Control of Disease
por: Verrua, Elisa, et al.
Publicado: (2014)

Regulatory subunits of PKA define an axis of cellular proliferation/differentiation in ovarian cancer cells
por: Cheadle, Chris, et al.
Publicado: (2008)

Plasmodium falciparum Regulatory Subunit of cAMP-Dependent PKA and Anion Channel Conductance
por: Merckx, Anaïs, et al.
Publicado: (2008)

The RIIbeta-subunit of protein kinase A (PKA) inhibits c-fos synthesis in T cells
por: Mishra, N, et al.
Publicado: (2001)

PKA regulatory IIα subunit is essential for PGD(2)-mediated resolution of inflammation
por: Kong, Deping, et al.
Publicado: (2016)

PKA-RII subunit phosphorylation precedes activation by cAMP and regulates activity termination
por: Isensee, Jörg, et al.
Publicado: (2018)

Phosphorylation and Dephosphorylation of Tau Protein by the Catalytic Subunit of PKA, as Probed by Electrophoretic Mobility Retard
por: Benítez, María J., et al.
Publicado: (2021)

Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits
por: Arveseth, Corvin D., et al.
Publicado: (2021)

Dopamine and Somatostatin Analogues Resistance of Pituitary Tumors: Focus on Cytoskeleton Involvement
por: Peverelli, Erika, et al.
Publicado: (2015)

PKA Cα subunit mutation triggers caspase-dependent RIIβ subunit degradation via Ser(114) phosphorylation
por: Weigand, Isabel, et al.
Publicado: (2021)

Modulation of Murine Olivary Connexin 36 Gap Junctions by PKA and CaMKII
por: Bazzigaluppi, Paolo, et al.
Publicado: (2017)

ColXV promotes adipocyte differentiation via inhibiting DNA methylation and cAMP/PKA pathway in mice
por: Liu, Guannv, et al.
Publicado: (2017)

DRD2 Agonist Cabergoline Abolished the Escape Mechanism Induced by mTOR Inhibitor Everolimus in Tumoral Pituitary Cells
por: Mangili, Federica, et al.
Publicado: (2022)

PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades
por: Stefan, Eduard, et al.
Publicado: (2011)

The PKA-C3 catalytic subunit is required in two pairs of interneurons for successful mating of Drosophila
por: Cassar, Marlène, et al.
Publicado: (2018)

Antenatal Microbial Colonization of Mammalian Gut
por: Borghi, Elisa, et al.
Publicado: (2018)

Thyroid-Stimulating Hormone Inhibits Adipose Triglyceride Lipase in 3T3-L1 Adipocytes through the PKA Pathway
por: Jiang, Dongqing, et al.
Publicado: (2015)

Sinapic acid induces the expression of thermogenic signature genes and lipolysis through activation of PKA/CREB signaling in brown adipocytes
por: Hossain, Monir, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ddgn36c813ncrn12oapbb5t4jg