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Dilution and the theoretical description of growth-rate dependent gene expression

Expression of a gene is not only tuned by direct regulation, but also affected by the global physiological state of the (host) cell. This global dependence complicates the quantitative understanding of gene regulation and the design of synthetic gene circuits. In bacteria these global effects can of...

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Detalles Bibliográficos
Autores principales: Hintsche, Marius, Klumpp, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847955/
https://www.ncbi.nlm.nih.gov/pubmed/24041253
http://dx.doi.org/10.1186/1754-1611-7-22