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Cancer Specificity of Promoters of the Genes Involved in Cell Proliferation Control

Core promoters with adjacent regions of the human genes CDC6, POLD1, CKS1B, MCM2, and PLK1 were cloned into a pGL3 vector in front of the Photinus pyrails gene Luc in order to study the tumor specificity of the promoters. The cloned promoters were compared in their ability to direct luciferase expre...

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Detalles Bibliográficos
Autores principales: Kashkin, K. N., Chernov, I. P., Stukacheva, E. A., Kopantzev, E. P., Monastyrskaya, G. S., Uspenskaya, N. Ya., Sverdlov, E. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848069/
https://www.ncbi.nlm.nih.gov/pubmed/24303203