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Investigations of Homologous Recombination Pathways and Their Regulation

The DNA double-strand break (DSB), arising from exposure to ionizing radiation or various chemotherapeutic agents or from replication fork collapse, is among the most dangerous of chromosomal lesions. DSBs are highly cytotoxic and can lead to translocations, deletions, duplications, or mutations if...

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Detalles Bibliográficos
Autores principales: Daley, James M., Kwon, YoungHo, Niu, Hengyao, Sung, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848099/
https://www.ncbi.nlm.nih.gov/pubmed/24348209