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Aggravation of myocardial dysfunction by injurious mechanical ventilation in LPS-induced pneumonia in rats

BACKGROUND: Mechanical ventilation (MV) may cause ventilator-induced lung injury (VILI) and may thereby contribute to fatal multiple organ failure. We tested the hypothesis that injurious MV of lipopolysaccharide (LPS) pre-injured lungs induces myocardial inflammation and further dysfunction ex vivo...

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Detalles Bibliográficos
Autores principales: Smeding, Lonneke, Kuiper, Jan Willem, Plötz, Frans B, Kneyber, Martin CJ, Groeneveld, AB Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848739/
https://www.ncbi.nlm.nih.gov/pubmed/24047433
http://dx.doi.org/10.1186/1465-9921-14-92