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Suppression of protein kinase C theta contributes to enhanced myogenesis In vitro via IRS1 and ERK1/2 phosphorylation

BACKGROUND: Differentiation and fusion of skeletal muscle myoblasts into multi-nucleated myotubes is required for neonatal development and regeneration in adult skeletal muscle. Herein, we report novel findings that protein kinase C theta (PKCθ) regulates myoblast differentiation via phosphorylation...

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Detalles Bibliográficos
Autores principales: Marino, Joseph S, Hinds, Terry D, Potter, Rachael A, Ondrus, Eric, Onion, Jeremy L, Dowling, Abigail, McLoughlin, Thomas J, Sanchez, Edwin R, Hill, Jennifer W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848841/
https://www.ncbi.nlm.nih.gov/pubmed/24053798
http://dx.doi.org/10.1186/1471-2121-14-39