Exosome derived from epigallocatechin gallate treated breast cancer cells suppresses tumor growth by inhibiting tumor-associated macrophage infiltration and M2 polarization

BACKGROUND: Tumor-associated macrophages (TAM) play an important role in tumor microenvironment. Particularly, M2 macrophages contribute to tumor progression, depending on the expression of NF-κB. Tumor-derived exosomes can modulate tumor microenvironment by transferring miRNAs to immune cells. Epig...

Descripción completa

Detalles Bibliográficos
Autores principales: Jang, Ji-Young, Lee, Jong-Kuen, Jeon, Yoon-Kyung, Kim, Chul-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848851/
https://www.ncbi.nlm.nih.gov/pubmed/24044575
http://dx.doi.org/10.1186/1471-2407-13-421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848851/
https://www.ncbi.nlm.nih.gov/pubmed/24044575
http://dx.doi.org/10.1186/1471-2407-13-421

Ejemplares similares