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Distinct polyadenylation landscapes of diverse human tissues revealed by a modified PA-seq strategy

BACKGROUND: Polyadenylation is a key regulatory step in eukaryotic gene expression and one of the major contributors of transcriptome diversity. Aberrant polyadenylation often associates with expression defects and leads to human diseases. RESULTS: To better understand global polyadenylation regulat...

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Detalles Bibliográficos
Autores principales: Ni, Ting, Yang, Yanqin, Hafez, Dina, Yang, Wenjing, Kiesewetter, Kurtis, Wakabayashi, Yoshi, Ohler, Uwe, Peng, Weiqun, Zhu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848854/
https://www.ncbi.nlm.nih.gov/pubmed/24025092
http://dx.doi.org/10.1186/1471-2164-14-615