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Distinct polyadenylation landscapes of diverse human tissues revealed by a modified PA-seq strategy
BACKGROUND: Polyadenylation is a key regulatory step in eukaryotic gene expression and one of the major contributors of transcriptome diversity. Aberrant polyadenylation often associates with expression defects and leads to human diseases. RESULTS: To better understand global polyadenylation regulat...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848854/ https://www.ncbi.nlm.nih.gov/pubmed/24025092 http://dx.doi.org/10.1186/1471-2164-14-615 |