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TRAF4 Is a Novel Phosphoinositide-Binding Protein Modulating Tight Junctions and Favoring Cell Migration

Tumor necrosis factor (TNF) receptor-associated factor 4 (TRAF4) is frequently overexpressed in carcinomas, suggesting a specific role in cancer. Although TRAF4 protein is predominantly found at tight junctions (TJs) in normal mammary epithelial cells (MECs), it accumulates in the cytoplasm of malig...

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Detalles Bibliográficos
Autores principales: Rousseau, Adrien, McEwen, Alastair G., Poussin-Courmontagne, Pierre, Rognan, Didier, Nominé, Yves, Rio, Marie-Christine, Tomasetto, Catherine, Alpy, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848981/
https://www.ncbi.nlm.nih.gov/pubmed/24311986
http://dx.doi.org/10.1371/journal.pbio.1001726