Gemcitabine and carboplatin demonstrate synergistic cytotoxicity in cervical cancer cells by inhibiting DNA synthesis and increasing cell apoptosis

BACKGROUND: The present study aims to investigate the subunit expression and enzyme activity of ribonucleotide reductase in cervical cancer patients, and detect the combined effect of the ribonucleotide reductase inhibitor gemcitabine and the chemotherapeutic agent carboplatin on cervical cancer cel...

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Detalles Bibliográficos
Autores principales: Jin, Guixiu, Zhao, Jing, Qi, Hongyan, Lou, Meng, Liu, Xia, Qu, Yu, Zhao, Lingjun, Zhang, Weifeng, Shao, Jimin, Zhong, Huizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848983/
https://www.ncbi.nlm.nih.gov/pubmed/24348048
http://dx.doi.org/10.2147/OTT.S54217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848983/
https://www.ncbi.nlm.nih.gov/pubmed/24348048
http://dx.doi.org/10.2147/OTT.S54217

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