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Gemcitabine and carboplatin demonstrate synergistic cytotoxicity in cervical cancer cells by inhibiting DNA synthesis and increasing cell apoptosis
BACKGROUND: The present study aims to investigate the subunit expression and enzyme activity of ribonucleotide reductase in cervical cancer patients, and detect the combined effect of the ribonucleotide reductase inhibitor gemcitabine and the chemotherapeutic agent carboplatin on cervical cancer cel...
Autores principales: | Jin, Guixiu, Zhao, Jing, Qi, Hongyan, Lou, Meng, Liu, Xia, Qu, Yu, Zhao, Lingjun, Zhang, Weifeng, Shao, Jimin, Zhong, Huizhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848983/ https://www.ncbi.nlm.nih.gov/pubmed/24348048 http://dx.doi.org/10.2147/OTT.S54217 |
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