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Co-Transplantation of GDNF-Overexpressing Neural Stem Cells and Fetal Dopaminergic Neurons Mitigates Motor Symptoms in a Rat Model of Parkinson’s Disease

Striatal transplantation of dopaminergic (DA) neurons or neural stem cells (NSCs) has been reported to improve the symptoms of Parkinson’s disease (PD), but the low rate of cell survival, differentiation, and integration in the host brain limits the therapeutic efficacy. We investigated the therapeu...

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Detalles Bibliográficos
Autores principales: Deng, Xingli, Liang, Yuanxin, Lu, Hua, Yang, Zhiyong, Liu, Ru’en, Wang, Jinkun, Song, Xiaobin, Long, Jiang, Li, Yu, Lei, Deqiang, Feng, Zhongtang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849044/
https://www.ncbi.nlm.nih.gov/pubmed/24312503
http://dx.doi.org/10.1371/journal.pone.0080880