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Co-Transplantation of GDNF-Overexpressing Neural Stem Cells and Fetal Dopaminergic Neurons Mitigates Motor Symptoms in a Rat Model of Parkinson’s Disease
Striatal transplantation of dopaminergic (DA) neurons or neural stem cells (NSCs) has been reported to improve the symptoms of Parkinson’s disease (PD), but the low rate of cell survival, differentiation, and integration in the host brain limits the therapeutic efficacy. We investigated the therapeu...
Autores principales: | Deng, Xingli, Liang, Yuanxin, Lu, Hua, Yang, Zhiyong, Liu, Ru’en, Wang, Jinkun, Song, Xiaobin, Long, Jiang, Li, Yu, Lei, Deqiang, Feng, Zhongtang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849044/ https://www.ncbi.nlm.nih.gov/pubmed/24312503 http://dx.doi.org/10.1371/journal.pone.0080880 |
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