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Detection of the GPI-anchorless prion protein fragment PrP226* in human brain

BACKGROUND: The accumulation of the misfolded forms of cellular prion protein, i.e. prions (PrP(Sc)), in the brain is one of the crucial characteristics of fatal neurodegenerative disorders, called transmissible spongiform encephalopathies (TSEs). Cellular prion protein is normally linked to the cel...

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Detalles Bibliográficos
Autores principales: Dvorakova, Eva, Vranac, Tanja, Janouskova, Olga, Černilec, Maja, Koren, Simon, Lukan, Anja, Nováková, Jana, Matej, Radoslav, Holada, Karel, Čurin Šerbec, Vladka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849060/
https://www.ncbi.nlm.nih.gov/pubmed/24063733
http://dx.doi.org/10.1186/1471-2377-13-126