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The human transcriptome is enriched for miRNA-binding sites located in cooperativity-permitting distance

MiRNAs are short, non-coding RNAs that regulate gene expression post-transcriptionally through specific binding to mRNA. Deregulation of miRNAs is associated with various diseases and interference with miRNA function has proven therapeutic potential. Most mRNAs are thought to be regulated by multipl...

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Detalles Bibliográficos
Autores principales: Rinck, Andrea, Preusse, Martin, Laggerbauer, Bernhard, Lickert, Heiko, Engelhardt, Stefan, Theis, Fabian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849160/
https://www.ncbi.nlm.nih.gov/pubmed/23696004
http://dx.doi.org/10.4161/rna.24955