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The human transcriptome is enriched for miRNA-binding sites located in cooperativity-permitting distance
MiRNAs are short, non-coding RNAs that regulate gene expression post-transcriptionally through specific binding to mRNA. Deregulation of miRNAs is associated with various diseases and interference with miRNA function has proven therapeutic potential. Most mRNAs are thought to be regulated by multipl...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849160/ https://www.ncbi.nlm.nih.gov/pubmed/23696004 http://dx.doi.org/10.4161/rna.24955 |