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Dysregulation of the long non-coding RNA transcriptome in a Rett syndrome mouse model

Mecp2 is a transcriptional repressor protein that is mutated in Rett syndrome, a neurodevelopmental disorder that is the second most common cause of mental retardation in women. It has been shown that the loss of the Mecp2 protein in Rett syndrome cells alters the transcriptional silencing of coding...

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Detalles Bibliográficos
Autores principales: Petazzi, Paolo, Sandoval, Juan, Szczesna, Karolina, Jorge, Olga C., Roa, Laura, Sayols, Sergi, Gomez, Antonio, Huertas, Dori, Esteller, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849168/
https://www.ncbi.nlm.nih.gov/pubmed/23611944
http://dx.doi.org/10.4161/rna.24286