Knockdown of the C. elegans Kinome identifies Kinases required for normal protein Homeostasis, Mitochondrial network structure, and Sarcomere structure in muscle

BACKGROUND: Kinases are important signalling molecules for modulating cellular processes and major targets of drug discovery programs. However, functional information for roughly half the human kinome is lacking. We conducted three kinome wide, >90%, RNAi screens and epistasis testing of some ide...

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Detalles Bibliográficos
Autores principales: Lehmann, Susann, Bass, Joseph J, Szewczyk, Nathaniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849176/
https://www.ncbi.nlm.nih.gov/pubmed/24060339
http://dx.doi.org/10.1186/1478-811X-11-71

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849176/
https://www.ncbi.nlm.nih.gov/pubmed/24060339
http://dx.doi.org/10.1186/1478-811X-11-71

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