Cargando…

NK4 Antagonizes Tbx1/10 to Promote Cardiac versus Pharyngeal Muscle Fate in the Ascidian Second Heart Field

The heart and head muscles share common developmental origins and genetic underpinnings in vertebrates, including humans. Parts of the heart and cranio-facial musculature derive from common mesodermal progenitors that express NKX2-5, ISL1, and TBX1. This ontogenetic kinship is dramatically reflected...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Wei, Razy-Krajka, Florian, Siu, Eric, Ketcham, Alexandra, Christiaen, Lionel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849182/
https://www.ncbi.nlm.nih.gov/pubmed/24311985
http://dx.doi.org/10.1371/journal.pbio.1001725