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Acidic extracellular microenvironment and cancer

Acidic extracellular pH is a major feature of tumor tissue, extracellular acidification being primarily considered to be due to lactate secretion from anaerobic glycolysis. Clinicopathological evidence shows that transporters and pumps contribute to H(+) secretion, such as the Na(+)/H(+) exchanger,...

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Detalles Bibliográficos
Autores principales: Kato, Yasumasa, Ozawa, Shigeyuki, Miyamoto, Chihiro, Maehata, Yojiro, Suzuki, Atsuko, Maeda, Toyonobu, Baba, Yuh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849184/
https://www.ncbi.nlm.nih.gov/pubmed/24004445
http://dx.doi.org/10.1186/1475-2867-13-89