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Respiratory uncoupling by increased H(+) or K(+) flux is beneficial for heart mitochondrial turnover of reactive oxygen species but not for permeability transition

BACKGROUND: Ischemic preconditioning has been proposed to involve changes in mitochondrial H(+) and K(+) fluxes, in particular through activation of uncoupling proteins and ATP-sensitive K(+) channels (MitoK(ATP)). The objectives of the present study were to explore how increased H(+) and K(+) fluxe...

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Detalles Bibliográficos
Autores principales: Morota, Saori, Piel, Sarah, Hansson, Magnus J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849260/
https://www.ncbi.nlm.nih.gov/pubmed/24053891
http://dx.doi.org/10.1186/1471-2121-14-40