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Respiratory uncoupling by increased H(+) or K(+) flux is beneficial for heart mitochondrial turnover of reactive oxygen species but not for permeability transition
BACKGROUND: Ischemic preconditioning has been proposed to involve changes in mitochondrial H(+) and K(+) fluxes, in particular through activation of uncoupling proteins and ATP-sensitive K(+) channels (MitoK(ATP)). The objectives of the present study were to explore how increased H(+) and K(+) fluxe...
Autores principales: | Morota, Saori, Piel, Sarah, Hansson, Magnus J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849260/ https://www.ncbi.nlm.nih.gov/pubmed/24053891 http://dx.doi.org/10.1186/1471-2121-14-40 |
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