Adaptation of CD8 T Cell Responses to Changing HIV-1 Sequences in a Cohort of HIV-1 Infected Individuals Not Selected for a Certain HLA Allele

HIV evades CD8 T cell mediated pressure by viral escape mutations in targeted CD8 T cell epitopes. A viral escape mutation can lead to a decline of the respective CD8 T cell response. Our question was what happened after the decline of a CD8 T cell response and - in the case of viral escape – if a n...

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Detalles Bibliográficos
Autores principales: Roider, Julia, Kalteis, Anna-Lena, Vollbrecht, Thomas, Gloning, Lisa, Stirner, Renate, Henrich, Nadja, Bogner, Johannes R., Draenert, Rika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849264/
https://www.ncbi.nlm.nih.gov/pubmed/24312453
http://dx.doi.org/10.1371/journal.pone.0080045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849264/
https://www.ncbi.nlm.nih.gov/pubmed/24312453
http://dx.doi.org/10.1371/journal.pone.0080045

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