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Adaptation of CD8 T Cell Responses to Changing HIV-1 Sequences in a Cohort of HIV-1 Infected Individuals Not Selected for a Certain HLA Allele
HIV evades CD8 T cell mediated pressure by viral escape mutations in targeted CD8 T cell epitopes. A viral escape mutation can lead to a decline of the respective CD8 T cell response. Our question was what happened after the decline of a CD8 T cell response and - in the case of viral escape – if a n...
Autores principales: | Roider, Julia, Kalteis, Anna-Lena, Vollbrecht, Thomas, Gloning, Lisa, Stirner, Renate, Henrich, Nadja, Bogner, Johannes R., Draenert, Rika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849264/ https://www.ncbi.nlm.nih.gov/pubmed/24312453 http://dx.doi.org/10.1371/journal.pone.0080045 |
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