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Ursodeoxycholic Acid but Not Tauroursodeoxycholic Acid Inhibits Proliferation and Differentiation of Human Subcutaneous Adipocytes

Stress of endoplasmic reticulum (ERS) is one of the molecular triggers of adipocyte dysfunction and chronic low inflammation accompanying obesity. ERS can be alleviated by chemical chaperones from the family of bile acids (BAs). Thus, two BAs currently used to treat cholestasis, ursodeoxycholic and...

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Detalles Bibliográficos
Autores principales: Mališová, Lucia, Kováčová, Zuzana, Koc, Michal, Kračmerová, Jana, Štich, Vladimír, Rossmeislová, Lenka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849437/
https://www.ncbi.nlm.nih.gov/pubmed/24312631
http://dx.doi.org/10.1371/journal.pone.0082086