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Sequence and structure based models of HIV-1 protease and reverse transcriptase drug resistance
BACKGROUND: Successful management of chronic human immunodeficiency virus type 1 (HIV-1) infection with a cocktail of antiretroviral medications can be negatively affected by the presence of drug resistant mutations in the viral targets. These targets include the HIV-1 protease (PR) and reverse tran...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849442/ https://www.ncbi.nlm.nih.gov/pubmed/24268064 http://dx.doi.org/10.1186/1471-2164-14-S4-S3 |