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Critical role of CCDC6 in the neoplastic growth of testicular germ cell tumors

BACKGROUND: DNA damage response has been clearly described as an anti-cancer barrier in early human tumorigenesis. Moreover, interestingly, testicular germ cell tumors (TGCTs) have been reported to lack the DNA Damage Response (DDR) pathway activation. CCDC6 is a pro-apoptotic phosphoprotein substra...

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Detalles Bibliográficos
Autores principales: Staibano, Stefania, Ilardi, Gennaro, Leone, Vincenza, Luise, Chiara, Merolla, Francesco, Esposito, Francesco, Morra, Francesco, Siano, Maria, Franco, Renato, Fusco, Alfredo, Chieffi, Paolo, Celetti, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849521/
https://www.ncbi.nlm.nih.gov/pubmed/24059746
http://dx.doi.org/10.1186/1471-2407-13-433