Context-dependent interpretation of the prognostic value of BRAF and KRAS mutations in colorectal cancer

BACKGROUND: The mutation status of the BRAF and KRAS genes has been proposed as prognostic biomarker in colorectal cancer. Of them, only the BRAF V600E mutation has been validated independently as prognostic for overall survival and survival after relapse, while the prognostic value of KRAS mutation...

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Detalles Bibliográficos
Autores principales: Popovici, Vlad, Budinska, Eva, Bosman, Fred T, Tejpar, Sabine, Roth, Arnaud D, Delorenzi, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849526/
https://www.ncbi.nlm.nih.gov/pubmed/24073892
http://dx.doi.org/10.1186/1471-2407-13-439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849526/
https://www.ncbi.nlm.nih.gov/pubmed/24073892
http://dx.doi.org/10.1186/1471-2407-13-439

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