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Context-dependent interpretation of the prognostic value of BRAF and KRAS mutations in colorectal cancer
BACKGROUND: The mutation status of the BRAF and KRAS genes has been proposed as prognostic biomarker in colorectal cancer. Of them, only the BRAF V600E mutation has been validated independently as prognostic for overall survival and survival after relapse, while the prognostic value of KRAS mutation...
Autores principales: | Popovici, Vlad, Budinska, Eva, Bosman, Fred T, Tejpar, Sabine, Roth, Arnaud D, Delorenzi, Mauro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849526/ https://www.ncbi.nlm.nih.gov/pubmed/24073892 http://dx.doi.org/10.1186/1471-2407-13-439 |
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