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How reliable is the linear noise approximation of gene regulatory networks?

BACKGROUND: The linear noise approximation (LNA) is commonly used to predict how noise is regulated and exploited at the cellular level. These predictions are exact for reaction networks composed exclusively of first order reactions or for networks involving bimolecular reactions and large numbers o...

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Detalles Bibliográficos
Autores principales: Thomas, Philipp, Matuschek, Hannes, Grima, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849541/
https://www.ncbi.nlm.nih.gov/pubmed/24266939
http://dx.doi.org/10.1186/1471-2164-14-S4-S5