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Implications and limitations of cellular reprogramming for psychiatric drug development

Human-induced pluripotent stem cells (hiPSCs) derived from somatic cells of patients have opened possibilities for in vitro modeling of the physiology of neural (and other) cells in psychiatric disease states. Issues in early stages of technology development include (1) establishing a library of cel...

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Detalles Bibliográficos
Autores principales: Tobe, Brian T D, Brandel, Michael G, Nye, Jeffrey S, Snyder, Evan Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849573/
https://www.ncbi.nlm.nih.gov/pubmed/24232258
http://dx.doi.org/10.1038/emm.2013.124