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Amyloid-β oligomers regulate the properties of human neural stem cells through GSK-3β signaling

Alzheimer's disease (AD) is the most common cause of age-related dementia. The neuropathological hallmarks of AD include extracellular deposition of amyloid-β peptides and neurofibrillary tangles that lead to intracellular hyperphosphorylated tau in the brain. Soluble amyloid-β oligomers are th...

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Detalles Bibliográficos
Autores principales: Lee, Il-Shin, Jung, Kwangsoo, Kim, Il-Sun, Park, Kook In
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849574/
https://www.ncbi.nlm.nih.gov/pubmed/24232259
http://dx.doi.org/10.1038/emm.2013.125