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Amyloid-β oligomers regulate the properties of human neural stem cells through GSK-3β signaling
Alzheimer's disease (AD) is the most common cause of age-related dementia. The neuropathological hallmarks of AD include extracellular deposition of amyloid-β peptides and neurofibrillary tangles that lead to intracellular hyperphosphorylated tau in the brain. Soluble amyloid-β oligomers are th...
Autores principales: | Lee, Il-Shin, Jung, Kwangsoo, Kim, Il-Sun, Park, Kook In |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849574/ https://www.ncbi.nlm.nih.gov/pubmed/24232259 http://dx.doi.org/10.1038/emm.2013.125 |
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