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Genome-wide modeling of complex phenotypes in Caenorhabditis elegans and Drosophila melanogaster

BACKGROUND: The genetic and molecular basis for many intermediate and end stage phenotypes in model systems such as C. elegans and D. melanogaster has long been known to involve pleiotropic effects and complex multigenic interactions. Gene sets are groups of genes that contribute to multiple biologi...

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Detalles Bibliográficos
Autores principales: De, Supriyo, Zhang, Yongqing, Wolkow, Catherine A, Zou, Sige, Goldberg, Ilya, Becker, Kevin G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849582/
https://www.ncbi.nlm.nih.gov/pubmed/23984798
http://dx.doi.org/10.1186/1471-2164-14-580