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Integration of mechanical and chemical signals by YAP and TAZ transcription coactivators
YAP and TAZ are transcription coactivators and effectors of the Hippo pathway, which play a key role in organ size control. Through interaction with transcription factors such as TEADs, they activate gene transcription and thus promote cell proliferation, inhibit apoptosis, and regulate cell differe...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849657/ https://www.ncbi.nlm.nih.gov/pubmed/23985334 http://dx.doi.org/10.1186/2045-3701-3-33 |