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Anoctamin 1 Mediates Thermal Pain as a Heat Sensor

Vertebrates can sense and avoid noxious heat that evokes pain. Many thermoTRP channels are associated with temperature sensation. TRPV1 is a representative ion channel that is activated by noxious heat. Anoctamin 1 (ANO1) is a Cl- channel activated by calcium that is highly expressed in small sensor...

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Detalles Bibliográficos
Autores principales: Cho, Hawon, Oh, Uhtaek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849789/
https://www.ncbi.nlm.nih.gov/pubmed/24396339
http://dx.doi.org/10.2174/1570159X113119990038