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Reverse translation of the rodent 5C-CPT reveals that the impaired attention of people with schizophrenia is similar to scopolamine-induced deficits in mice

Attentional dysfunction in schizophrenia (SZ) is a core deficit that contributes to multiple cognitive deficits and the resulting functional disability. However, developing procognitive therapeutics for neuropsychiatric disorders have been limited by a ‘translational gap'—a lack of cognitive pa...

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Detalles Bibliográficos
Autores principales: Young, J W, Geyer, M A, Rissling, A J, Sharp, R F, Eyler, L T, Asgaard, G L, Light, G A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849961/
https://www.ncbi.nlm.nih.gov/pubmed/24217494
http://dx.doi.org/10.1038/tp.2013.82