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Reverse translation of the rodent 5C-CPT reveals that the impaired attention of people with schizophrenia is similar to scopolamine-induced deficits in mice
Attentional dysfunction in schizophrenia (SZ) is a core deficit that contributes to multiple cognitive deficits and the resulting functional disability. However, developing procognitive therapeutics for neuropsychiatric disorders have been limited by a ‘translational gap'—a lack of cognitive pa...
Autores principales: | Young, J W, Geyer, M A, Rissling, A J, Sharp, R F, Eyler, L T, Asgaard, G L, Light, G A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849961/ https://www.ncbi.nlm.nih.gov/pubmed/24217494 http://dx.doi.org/10.1038/tp.2013.82 |
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