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Canonical Wnt Signaling Promotes Early Hematopoietic Progenitor Formation and Erythroid Specification during Embryonic Stem Cell Differentiation

The generation of hematopoietic stem cells (HSCs) during development is a complex process linked to morphogenic signals. Understanding this process is important for regenerative medicine applications that require in vitro production of HSC. In this study we investigated the effects of canonical Wnt/...

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Detalles Bibliográficos
Autores principales: Tarafdar, Anuradha, Dobbin, Edwina, Corrigan, Pamela, Freeburn, Robin, Wheadon, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850021/
https://www.ncbi.nlm.nih.gov/pubmed/24324557
http://dx.doi.org/10.1371/journal.pone.0081030