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Development of transgenic mice expressing a coronavirus-specific public CD4 T cell receptor

Mice that are transgenic (Tg) for T cell receptor (TCR) expression are used extensively to analyze longitudinal T cell responses during effector and memory phases of the T cell response. Generation of TCR Tg mice generally requires T cell stimulation and cloning in vitro prior to amplification, proc...

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Detalles Bibliográficos
Autores principales: Zhao, Jingxian, Fett, Craig, Pewe, Lecia, Zhao, Jincun, Perlman, Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850057/
https://www.ncbi.nlm.nih.gov/pubmed/23928495
http://dx.doi.org/10.1016/j.jim.2013.07.011