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Development of transgenic mice expressing a coronavirus-specific public CD4 T cell receptor
Mice that are transgenic (Tg) for T cell receptor (TCR) expression are used extensively to analyze longitudinal T cell responses during effector and memory phases of the T cell response. Generation of TCR Tg mice generally requires T cell stimulation and cloning in vitro prior to amplification, proc...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850057/ https://www.ncbi.nlm.nih.gov/pubmed/23928495 http://dx.doi.org/10.1016/j.jim.2013.07.011 |