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Exploiting the bad eating habits of Ras-driven cancers

Oncogenic Ras promotes glucose fermentation and glutamine use to supply central carbon metabolism, but how and why have only emerged recently. Ras-mediated metabolic reprogramming generates building blocks for growth and promotes antioxidant defense. To fuel metabolic pathways, Ras scavenges extrace...

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Detalles Bibliográficos
Autor principal: White, Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850091/
https://www.ncbi.nlm.nih.gov/pubmed/24115766
http://dx.doi.org/10.1101/gad.228122.113