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Peanut Allergen Threshold Study (PATS): validation of eliciting doses using a novel single-dose challenge protocol

BACKGROUND: The eliciting dose (ED) for a peanut allergic reaction in 5% of the peanut allergic population, the ED05, is 1.5 mg of peanut protein. This ED05 was derived from oral food challenges (OFC) that use graded, incremental doses administered at fixed time intervals. Individual patients’ thres...

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Detalles Bibliográficos
Autores principales: Zurzolo, Giovanni A, Allen, Katrina J, Taylor, Steve L, Shreffler, Wayne G, Baumert, Joseph L, Tang, Mimi L K, Gurrin, Lyle C, Mathai, Michael L, Nordlee, Julie A, DunnGalvin, Audrey, Hourihane, Jonathan O’B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850217/
https://www.ncbi.nlm.nih.gov/pubmed/24028324
http://dx.doi.org/10.1186/1710-1492-9-35