A CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes

The tumor microenvironment is characterized by of high levels of extracellular nucleotides that are metabolized through the dynamic and sequential action of cell surface enzymes (ectoenzymes). These ectoenzymes operate according to their spatial arrangement, as part of (1) continuous (molecules on t...

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Detalles Bibliográficos
Autores principales: Horenstein, Alberto L, Chillemi, Antonella, Zaccarello, Gianluca, Bruzzone, Santina, Quarona, Valeria, Zito, Andrea, Serra, Sara, Malavasi, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850273/
https://www.ncbi.nlm.nih.gov/pubmed/24319640
http://dx.doi.org/10.4161/onci.26246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850273/
https://www.ncbi.nlm.nih.gov/pubmed/24319640
http://dx.doi.org/10.4161/onci.26246

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