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Lenalidomide monotherapy and in combination with cytarabine, daunorubicin and etoposide for high-risk myelodysplasia and acute myeloid leukaemia with chromosome 5 abnormalities()

Patients with high risk myelodysplasia (HR-MDS) and acute myeloid leukaemia (AML) with chromosomal changes involving deletion of the long arm of chromosome 5 (del5q), especially with complex karyotype, rarely have a durable response to combination chemotherapy. In the subgroup with monosomal karyoty...

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Detalles Bibliográficos
Autores principales: Dennis, M., Culligan, D., Karamitros, D., Vyas, P., Johnson, P., Russell, N.H., Cavenagh, J., Szubert, A., Hartley, S., Brown, J., Bowen, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850387/
https://www.ncbi.nlm.nih.gov/pubmed/24371786
http://dx.doi.org/10.1016/j.lrr.2013.07.003