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Lenalidomide monotherapy and in combination with cytarabine, daunorubicin and etoposide for high-risk myelodysplasia and acute myeloid leukaemia with chromosome 5 abnormalities()
Patients with high risk myelodysplasia (HR-MDS) and acute myeloid leukaemia (AML) with chromosomal changes involving deletion of the long arm of chromosome 5 (del5q), especially with complex karyotype, rarely have a durable response to combination chemotherapy. In the subgroup with monosomal karyoty...
Autores principales: | Dennis, M., Culligan, D., Karamitros, D., Vyas, P., Johnson, P., Russell, N.H., Cavenagh, J., Szubert, A., Hartley, S., Brown, J., Bowen, D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850387/ https://www.ncbi.nlm.nih.gov/pubmed/24371786 http://dx.doi.org/10.1016/j.lrr.2013.07.003 |
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