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The Different Roles of hRAD50 in Microsatellite Stable and Unstable Colorectal Cancers

RAD50 protein is essential for DNA double-strand break repair and maintaining genomic integrity. In this study, we investigated the clinicopathological significance of hRAD50 expression and mutation in microsatellite stable (MSS) and unstable (MSI) colorectal cancers (CRCs). hRAD50 expression was ex...

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Detalles Bibliográficos
Autores principales: Gao, Jingfang, Zhang, Hong, Arbman, Gunnar, Sun, Xiao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850595/
https://www.ncbi.nlm.nih.gov/pubmed/18219098
http://dx.doi.org/10.1155/2008/724796